The Design and Analysis of Sequential Clinical Trials, 2.Rev.Ed.
The Design and Analysis of Sequential Clinical Trials, 2.Rev.Ed. Books
Product Description
This book details all aspects of sequential clinical trials from preliminary plotting, through the monitoring of the trial, to the final analysis of the consequences. Emphasis is placed on the triangular test and other procedures based on honest line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.
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