The Combinatorial Index
The Combinatorial Index Books
Product Description
With the explosion of combinatorial solid-phase methods, access to in rank has become one of the main barriers facing a synthetic chemist who is contemplating a combinatorial approach to a medicinal chemistry problem. The Combinatorial Index is an resolution to that problem. This compendium of methods from the primary literature provides quick and convenient access to reliable synthetic transformations as well as in rank on linkers and analytical methods. Each synthetic course of action is preceded by a section entitled”Points of Interest,”which highlights the strengths and weaknesses of the various studies. The index also covers the use of solution-based synthesis for the generation of molecular diversity.
Key Features
* Organized for rapid retrieval of published in rank on classes of synthetic transformations, linkers, and analytical methods
* Serves as a laboratory manual for bench chemists
* Includes a chapter on linkers to help in choice of linking strategy
* Discusses strengths and limitations of the various methods
* Contains a structural index showing functional group transformations in solid-phase synthesis
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