Foundations of Cellular Neurophysiology
Foundations of Cellular Neurophysiology Books
Product Description
with simulations and illustrations by Richard Gray Problem solving is an obligatory part of learning a quantitative science such as neurophysiology. This text for graduate and advanced undergraduate students in neuroscience, physiology, biophysics, and computational neuroscience provides comprehensive, mathematically sophisticated descriptions of modern principles of cellular neurophysiology. It is the only neurophysiology text that gives detailed derivations of equations, worked examples, and homework problem sets (with complete answers). Developed from notes for the course that the authors have taught since 1983, Foundations of Cellular Neurophysiology covers cellular neurophysiology (also some material at the molecular and systems levels) from its corporal and mathematical foundations in a way that is far more rigorous than other commonly used texts in this area. Errata
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Haven’t read much of the book. It was required for class. Helpful to learn certain processes so far.
Rating: 5 / 5
You don’t really have to hold a degree in mathematics or physics to know cellular biophysics quantitavely; at least not with this book.
Clearly written, concise, self-contained, starts with the very basic knowledge of ion transport through semi-permeable membranes, moves to electrical properties of membranes, and then to passive and active properties of neuronal membranes, all in a very didactic and intuitive approach.
Of unique interest are the chapters on stochastic analysis and formulation of single channel function, and on the relationship between calcium dynamics and transmitter release.
This text is essential for students interested in pursuing graduate studies in electrophysiology, cellular neuroscience, and in computational neuroscience.
Rating: 4 / 5
The book cover boasts that this is the only book with through discussions in mathematical equations, etc. Indeed! Except that there are other mathematically oriented books with kindly worked out examples. Some concepts, such as deriviation of the cable equation, were wonderfully presented. But, no attempt is made to obtain the solution. To reckon about it, that might have been an apt choice, for a physiologist does not have to know all the mathematics. But, the Rall develop (Sec. 3.5) should have been approached in analogy with impedance matching. A unique feature of this book was to some extent detailed discussion of the Stochastic nature of ion channels. This is a excellent book, I judge. Overall, mathematics is thorough and abstract concepts are well chewed over.
Rating: 4 / 5
This book is chock full of equations as regards the Hodgkin-Huxley Develop, Kinetics of Ionic Channels, Presynaptic & Postsynaptic Transmission, LTP, LTD, quantum vesicular release and reuptake, & a “inadequate” neural net theory. There are a superfluity of ‘end of chapter’ problems with derivations & applications to solve. The book is going to be confusing and tedious, even for computationally trained neuroscientists. For me, this book is a reference only. The format is similar to Thomas Weiss’ Cellular Biophysics 2 Volume Set. There is too much on the Hodgkin-Huxley Develop which is very vital historically, but of less interest today than it was in the 1960s. The authors also use cable theory to develop neuronal & dendritic function.
Rating: 4 / 5
This was the assigned text for a small section on electrophysiology in my first year graduate neuroscience course. I did not have a math or electronics background, but had worked in a neurophys lab for two years. I managed to learn stuff from this book, but it was hard work and I couldn’t have done it without my lecturer and classmates. It’s evident that the authors really know their stuff, but being able to clarify it to novices is another thing… And I agree with the other reviewer who noted that the index is *absolutely* useless, nearly random lists of page numbers after topics…
Unless you have to buy this book for a class, skip it (and if it is the text for a course, question your instructor why!!)- buy Molecular and Cellular Physiology of Neurons by Fain instead, it doesn’t cover as many topics, but breadth is no use if you can’t know the content. My department switched to the Fain text last year because so many people complained about Johnston et al.
Rating: 2 / 5