Exploration and Analysis of DNA Microarray and Protein Array Data
Exploration and Analysis of DNA Microarray and Protein Array Data Books
Product Description
A cold-edge guide to the analysis of DNA microarray data
Genomics is one of the major scientific revolutions of this century, and the use of microarrays to rapidly question numerous DNA samples has enabled scientists to make sense of mountains of genomic data through statistical analysis. Today, microarrays are being used in biomedical research to study such vital areas as a drug’s therapeutic value–or toxicity–and cancer-spreading patterns of gene activity.
Exploration and Analysis of DNA Microarray and Protein Array Data answers the need for a comprehensive, cold-edge overview of this vital and emerging field. The authors, seasoned researchers with extensive experience in both industry and academia, effectively outline all phases of this revolutionary analytical technique, from the preprocessing to the analysis stage.
Highlights of the text include:
- A review of basic molecular biology, followed by an introduction to microarrays and their preparation
- Chapters on processing scanned images and preprocessing microarray data
- Methods for identifying differentially expressed genes in comparative microarray experiments
- Discussions of gene and sample clustering and class prediction
- Extension of analysis methods to protein array data
Numerous exercises for self-study as well as data sets and a helpful collection of computational tools on the authors’ Web site make this vital text a valuable resource for both students and professionals in the field.
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