DNA Repair in Cancer Therapy

DNA Repair in Cancer Therapy Books

DNA Repair in Cancer Therapy

Product Description
A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors clarify in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now below development and close to clinical trials. The book captures-for both cancer researchers and involved oncologists dealing with token “relapse” or “drug resistance” phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either lonely or in combination with anticancer therapies.

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