Pharmacology

Mitosenes and Related Antitumor Drugs: Rational Design and Cytostatic Agents

Mitosenes and Correlated Antitumor Drugs: Rational Design and Cytostatic Agents Books

Product Description
G. Landes). Rotterdam Cancer Institute, The Netherlands. Text emphasizing the bioreductively activated compounds that fall into the mitosene category, for investigators.

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Modern Catalytic Methods for Organic Synthesis with Diazo Compounds: From Cyclopropanes to Ylides

Modern Catalytic Methods for Organic Synthesis with Diazo Compounds: From Cyclopropanes to Ylides Books

Product Description
This much-needed resource brings together a wealth of procedures for the synthesis and matter-of-fact use of diazocarbonyl compounds. It features methods for the preparation of vital catalysts and for applications of diazocarbonyl compounds within each of the main transformation categories-including in-depth coverage of cyclopropanation, C-H and X-H insertion, Wolff rearrangement, ylide formation, aromatic cycloaddition and substitution, and many other helpful reactions.

Written by leading experts in the field, this book contains cold-edge material on highly enantioselective transformations, and presents new ways of thought about diazocarbonyl compounds and their applications, from donor-acceptor cyclopropanes in organic synthesis to macrocyclic cyclopropanation.

Complete with illustrative examples of procedures in each chapter, clear diagrams, and a detailed bibliography, this matter-of-fact reference gives readers the tools they need to place diazocarbonyl compounds to work for their own projects-an invaluable source of guidance for synthetic organic chemists, chemical scientists, and advanced students.

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Mirena: The Levonorgestrel Intrauterine System: The New Contraceptive Option for Parous Women

Mirena: The Levonorgestrel Intrauterine System: The New Contraceptive Option for Parous Women Books

Product Description
This is the first clinical reference text on Mirena™ – the levonorgestrel intrauterine system (IUS) that has achieved fantastic success in the UK and Scandinavia since its first commercial release in Finland in 1990. Considered to be a new paradigm in contraception, Mirena™ offers very high and comfortable contraceptive efficacy with reduced menstrual pain and blood loss and minimal side effects. Mirena™ is said to offer an brilliant contraceptive choice for modern women, fitting in well with an active professional life, free choice of sport activities, and a spontaneous sex life. The book contains five authoritatively written chapters on 21st century contraception, effects of the levonorgestrel intrauterine system on the endometrium, menstrual bleeding pattern, perimenopausal contraception, and the safety profile of Mirena™ based on long-term experience. Includes bibliographic references and index. Publication Note: This volume is the proceedings of a symposium held at the XV FIGO World Congress of Gynecology and Obstetrics, Copenhagen, August, 1997.

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Mass Spectrometry in Biology and Medicine

Mass Spectrometry in Biology and Medicine Books

Product Description
Leading practitioners detail revolutionary new spectrometric techniques for the identification and covalent structural characterization of macromolecules, proteins, glycoconjugates, and nucleic acids. Based on the Fourth International Symposium on Mass Spectrometry in the Health and Life Sciences held in San Francisco in 1998, this invaluable book contains tested strategies for solving many significant biomedical research problems. The techniques use mass spectrometry, automated computer processing of spectral in rank, and gene, protein, and EST databases for genomic and proteomic correlations. Mass Spectrometry in Biology and Medicine offers a unique opportunity to explore and apply these new techniques of mass spectrometry that are revolutionizing the identification and structural characterization of proteins, carbohydrates, and nucleic acids.

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Human Toxicology

Human Toxicology Books

Product Description
This brilliant volume was calculated and edited with two major thoughts in mind: firstly, the field of clinical toxicology is changing and an acknowledgement of these changes is warranted; secondly, no comprehensive compilation of recently published case reports of, and clinical studies on, human poisonings is available, which is in sharp contrast to the closely correlated field of drug-induced side-effects.

The book focusses on issues of recent concern, or issues poorly documented in the past. It is vital that clinical toxicologists gain a better knowledge of all the available techniques of toxicological analysis. A better understanding of the way a sound interpretation of consequences should be conducted for the benefit of the patient’s management, and a comprehensive set of data on the kinetics of the most common pharmaceutical drugs and many chemicals is required.

Human Toxicology is a timely reference work which will be welcomed by a broad audience of toxicology professionals.

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Heparin-Binding Proteins

Heparin-Binding Proteins Books

Product Description
This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolism. Heparin-Binding Proteins introduces the general nature of interactions between heparinoids and proteins, and presents the role for these structures in their interactions with the proteins of the hemostatic mechanisms, fibroblasts growth factors, superoxide dismutase, and lipoproteins.

Key Features
* Covers cellular metabolism of heparinoid proteoglycans
* Written by a distinguished expert in the field of carbohydrate biochemistry
* Describes the roles of heparan sulfate proteoglycans in
* * Blood coagulation and fibrinolysis
* Lipoprotein metabolism
* Superoxide dismutase activity
* Fibroblast growth factor responses of cells

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The Headache Handbook: Diagnosis and Treatment

The Headache Handbook: Diagnosis and Treatment Books

Product Description
The Headache Handbook: Diagnosis and Treatment helps both generalist and specialist clinicians, including family practitioners, chiropractors, and neurologists, to know headache, possibly the most ubiquitous symptom in medicine. This comprehensive work covers the myriad of differences among headache patients and the need for right fact gathering and corporal and neurological examinations. Topics include anatomy and physiology of headache; evaluation and treatment of various headache types; interventional procedures; and manual medicine consultations.

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Hazardous Waste Compliance

Hazardous Waste Compliance Books

Product Description
Hazardous Waste Compliance concentrates on government set of laws as they relate to hazardous waste and other hazardous materials. The main focus of this book is on how to comply with these requirements as well as on other best management practices (BMP), which will make sure worker safety and business protection from the risk of the commercial penalties associated with set of laws breaches.

The authors provide the reader with helpful techniques to enhance worker protection and promote efficiency, productivity and cost effectiveness, by the side of with achieving the necessary quality standards for the work being performed. The authors further outline and define methods to help reduce worker injury and illness, the scope and application of HAZWOPER, and ways to implement hazardous material correlated requirements through enhancements of existing programs.

In addition, detailed discussion helps to provide methods to help promote consistency in health and safety program development for handling hazardous materials, encourage a high standard for health and safety, and share lessons learned to help provide approaches that have been implemented on hazardous waste and other sites.

Provides a comprehensive overview of regulatory requirements in the industry
Real-life experiences are presented in the form of case histories
A training aid for both new and experienced site workers

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Hazardous Gases Underground: Applications to Tunnel Engineering

Hazardous Gases Underground: Applications to Tunnel Engineering Books

Product Description
Applies detailed knowledge toward the design and construction of underground civil works projects. Develops critical skills for administration risk and designing reliable gas control measures within project time and cost constraints.

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Handbook of Estimation Methods in Ecotoxicology and Environmental Chemistry

Handbook of Estimation Methods in Ecotoxicology and Environmental Chemistry Books

Product Description
Slightly more than 100,000 chemicals are produced in such an quantity that they are threatening to the environment. These include common chemicals such as household cleaners, detergents, blusher, medicines, and pesticides. The Handbook of Estimation Methods in Ecotoxicology and Environmental Chemistry presents estimation methods for determining a number of physicochemical, biological, and toxicological parameters for these chemicals. Included is WinTox software, as estimation tool that is quick and simple to use; it provides a excellent initial estimate that can be further refined.

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