Caliciviruses: Molecular and Cellular Virology

Caliciviruses: Molecular and Cellular Virology Books

Product Description
Caliciviruses are positive-sense, single stranded RNA viruses containing four recognized genera: Norovirus, Sapovirus, Lagovirus, and Vesivirus. They are ubiquitous in the environment and are a major cause of disease in humans as well as many animals. Examples include Norwalk virus – a norovirus, plotting to be responsible for roughly 90% of epidemic, non-bacterial outbreaks of gastroenteritis in humans nearly the world. The lack of a apposite cell culture system for human caliciviruses has limited studies in previous decades, but the recent application of modern genomic technologies has revolutionized the field, leading to an explosion in calicivirus publications. In this book, a panel of experts distil the most vital up-to-date research findings in their respective calicivirus field of study, producing timely and comprehensive reviews. Each chapter gives the reader a brief introduction to the topic, followed by a descriptive discussion of the past and bestow research areas. Topics include: norovirus epidemiology * calicivirus contamination of the environment * genome organization and recombination, proteolytic cleavage, and viral proteins * viral protein structures * virus-host interactions * calicivirus reverse genetics and replicon systems * feline calicivirus * swine calicivirus * murine norovirus pathogenesis and immunity * murine norovirus translation, replication, and reverse genetics * and lagoviruses. This book will be essential reading for all virologists working on caliciviruses and correlated viruses and is not compulsory for all virology, immunology, and molecular biology laboratories.

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